The value of classifying interstitial pneumonitis in childhood according to defined histological patterns
Identifieur interne : 002787 ( Main/Exploration ); précédent : 002786; suivant : 002788The value of classifying interstitial pneumonitis in childhood according to defined histological patterns
Auteurs : A G Nicholson ; H. Kim [Corée du Sud] ; B. Corrin ; A. Bush [Royaume-Uni] ; R M Du Bois [Royaume-Uni] ; M. Rosenthal [Royaume-Uni] ; M N SheppardSource :
- Histopathology [ 0309-0167 ] ; 1998-09.
Abstract
Aims: Interstitial pneumonitis in children is very rare and most cases have been classified according to their counterparts in adults, although the term ‘chronic pneumonitis of infancy’ has recently been proposed for a particular pattern of interstitial lung disease in infants. We reviewed our paediatric cases of interstitial pneumonitis, first, to look at the spectrum of histological patterns found in this age group and, second, to determine whether the classification of such cases in childhood is both appropriate and worthwhile. Methods and results: Twenty‐five of 38 open lung biopsies showed an overlapping spectrum of interstitial pneumonitis, including three cases that fulfilled the histological criteria for chronic pneumonitis of infancy. There were 11 cases of reactive pulmonary lymphoid hyperplasia (either lymphoid interstitial pneumonitis or follicular bronchiolitis), five of which were associated with abnormalities of the immune system. Four cases were classified as desquamative interstitial pneumonitis and the remaining seven cases were classified as non‐specific interstitial pneumonitis. There were no cases with the histological features of usual interstitial pneumonitis. Most patients responded to steroids but tended to have a residual deficit in lung function. Mortality appeared to be associated with presentation at a young age. Conclusion: Classification of interstitial pneumonitis according to their adult counterparts is appropriate for this younger age group and can provide valuable information for the clinician. The term ‘chronic pneumonitis of infancy’ refers to a specific histological pattern, but whether it represents a separate disease or a reflection of pulmonary immaturity remains to be proven.
Url:
DOI: 10.1046/j.1365-2559.1998.00488.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000B70
- to stream Istex, to step Curation: 000B70
- to stream Istex, to step Checkpoint: 001591
- to stream Main, to step Merge: 002829
- to stream Main, to step Curation: 002787
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The value of classifying interstitial pneumonitis in childhood according to defined histological patterns</title><author><name sortKey="Nicholson, A G" sort="Nicholson, A G" uniqKey="Nicholson A" first="A G" last="Nicholson">A G Nicholson</name></author><author><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name></author><author><name sortKey="Corrin, B" sort="Corrin, B" uniqKey="Corrin B" first="B" last="Corrin">B. Corrin</name></author><author><name sortKey="Bush, A" sort="Bush, A" uniqKey="Bush A" first="A" last="Bush">A. Bush</name></author><author><name sortKey="Du Bois, R M" sort="Du Bois, R M" uniqKey="Du Bois R" first="R M" last="Du Bois">R M Du Bois</name></author><author><name sortKey="Rosenthal, M" sort="Rosenthal, M" uniqKey="Rosenthal M" first="M" last="Rosenthal">M. Rosenthal</name></author><author><name sortKey="Sheppard, M N" sort="Sheppard, M N" uniqKey="Sheppard M" first="M N" last="Sheppard">M N Sheppard</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BDED0BDB6A305C29599DB9AFA3889933ECE8DE52</idno><date when="1998" year="1998">1998</date><idno type="doi">10.1046/j.1365-2559.1998.00488.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-L3Z26JWP-4/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000B70</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000B70</idno><idno type="wicri:Area/Istex/Curation">000B70</idno><idno type="wicri:Area/Istex/Checkpoint">001591</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001591</idno><idno type="wicri:doubleKey">0309-0167:1998:Nicholson A:the:value:of</idno><idno type="wicri:Area/Main/Merge">002829</idno><idno type="wicri:Area/Main/Curation">002787</idno><idno type="wicri:Area/Main/Exploration">002787</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">The value of classifying interstitial pneumonitis in childhood according to defined histological patterns</title><author><name sortKey="Nicholson, A G" sort="Nicholson, A G" uniqKey="Nicholson A" first="A G" last="Nicholson">A G Nicholson</name><affiliation><wicri:noCountry code="no comma">Departments of Histopathology</wicri:noCountry></affiliation></author><author><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pathology, Korea University</wicri:regionArea><wicri:noRegion>Korea University</wicri:noRegion></affiliation></author><author><name sortKey="Corrin, B" sort="Corrin, B" uniqKey="Corrin B" first="B" last="Corrin">B. Corrin</name><affiliation><wicri:noCountry code="no comma">Departments of Histopathology</wicri:noCountry></affiliation></author><author><name sortKey="Bush, A" sort="Bush, A" uniqKey="Bush A" first="A" last="Bush">A. Bush</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Respiratory Medicine, Royal Brompton Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Du Bois, R M" sort="Du Bois, R M" uniqKey="Du Bois R" first="R M" last="Du Bois">R M Du Bois</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Respiratory Medicine, Royal Brompton Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Rosenthal, M" sort="Rosenthal, M" uniqKey="Rosenthal M" first="M" last="Rosenthal">M. Rosenthal</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Respiratory Medicine, Royal Brompton Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sheppard, M N" sort="Sheppard, M N" uniqKey="Sheppard M" first="M N" last="Sheppard">M N Sheppard</name><affiliation><wicri:noCountry code="no comma">Departments of Histopathology</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Histopathology</title><title level="j" type="alt">HISTOPATHOLOGY</title><idno type="ISSN">0309-0167</idno><idno type="eISSN">1365-2559</idno><imprint><biblScope unit="vol">33</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="203">203</biblScope><biblScope unit="page" to="211">211</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, U.K. and Cambridge, USA</pubPlace><date type="published" when="1998-09">1998-09</date></imprint><idno type="ISSN">0309-0167</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0309-0167</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Aims: Interstitial pneumonitis in children is very rare and most cases have been classified according to their counterparts in adults, although the term ‘chronic pneumonitis of infancy’ has recently been proposed for a particular pattern of interstitial lung disease in infants. We reviewed our paediatric cases of interstitial pneumonitis, first, to look at the spectrum of histological patterns found in this age group and, second, to determine whether the classification of such cases in childhood is both appropriate and worthwhile. Methods and results: Twenty‐five of 38 open lung biopsies showed an overlapping spectrum of interstitial pneumonitis, including three cases that fulfilled the histological criteria for chronic pneumonitis of infancy. There were 11 cases of reactive pulmonary lymphoid hyperplasia (either lymphoid interstitial pneumonitis or follicular bronchiolitis), five of which were associated with abnormalities of the immune system. Four cases were classified as desquamative interstitial pneumonitis and the remaining seven cases were classified as non‐specific interstitial pneumonitis. There were no cases with the histological features of usual interstitial pneumonitis. Most patients responded to steroids but tended to have a residual deficit in lung function. Mortality appeared to be associated with presentation at a young age. Conclusion: Classification of interstitial pneumonitis according to their adult counterparts is appropriate for this younger age group and can provide valuable information for the clinician. The term ‘chronic pneumonitis of infancy’ refers to a specific histological pattern, but whether it represents a separate disease or a reflection of pulmonary immaturity remains to be proven.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><noCountry><name sortKey="Corrin, B" sort="Corrin, B" uniqKey="Corrin B" first="B" last="Corrin">B. Corrin</name><name sortKey="Nicholson, A G" sort="Nicholson, A G" uniqKey="Nicholson A" first="A G" last="Nicholson">A G Nicholson</name><name sortKey="Sheppard, M N" sort="Sheppard, M N" uniqKey="Sheppard M" first="M N" last="Sheppard">M N Sheppard</name></noCountry><country name="Corée du Sud"><noRegion><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Bush, A" sort="Bush, A" uniqKey="Bush A" first="A" last="Bush">A. Bush</name></region><name sortKey="Du Bois, R M" sort="Du Bois, R M" uniqKey="Du Bois R" first="R M" last="Du Bois">R M Du Bois</name><name sortKey="Rosenthal, M" sort="Rosenthal, M" uniqKey="Rosenthal M" first="M" last="Rosenthal">M. Rosenthal</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002787 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002787 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:BDED0BDB6A305C29599DB9AFA3889933ECE8DE52
|texte= The value of classifying interstitial pneumonitis in childhood according to defined histological patterns
}}
| This area was generated with Dilib version V0.6.33. |  |